The FDA ARGOS database generates and publishes quality-controlled microbial reference genomes for diagnostic use, which enable ID-NGS developers to perform in silico validation of their workflows. FDA partnered with IGS in 2013 to provide microbial genome sequencing, analysis, and deposition to public databases in support of the ARGOS database.
Contributing Genomes to FDA-ARGOS:
Further population and curation of the database will support the success of FDA-ARGOS and promote adoption by the NGS community. The FDA-ARGOS team openly invites additional collaborators from the scientific community to assist in filling the gaps in this public resource. The FDA-ARGOS and collaborators are specifically searching for unique, hard to source microbes such as biothreat organisms, emerging pathogens, and clinically significant bacterial, viral, fungal, and parasitic genomes. The goal is to collect sequence information for a minimum of 5 isolates per species. These isolates will be sequenced using a combination of long-read and short-read technologies, assembled, annotated, and made publicly available.